Reproductive Immunology

Seeing a Reproductive Immunologist is not something that most people consider, or have even heard of. The practice is sometimes frowned upon by Reproductive Endocrinologists (what we typically refer to as fertility doctors).

The thing about it is, it’s still considered to be a relatively new practice with a bit of a dicey history.

At this point, we know that immune system dysfunction has been identified as a likely contributor to endometriosis, infertility, recurrent pregnancy loss, preeclampsia, and preterm delivery.

However, the amazingly complex nature of immune system function makes reproductive immunology an incredibly difficult field to understand, for clinicians and scientists, leading to skepticism and misinterpretation of data[1].

For women who have had no success with traditional fertility treatments, it’s a source of hope when there is no answer either as to why they aren’t able to get pregnant or why they can’t sustain a pregnancy.

Demystifying Reproductive Immunology

Reproductive immunology focuses on the maternal immune system.

The belief is that the female immune system could have an impact on implantation, as well as the growth and development of the fetus.

Basically, your immune system could see the growing baby as an attack on the immune system like a bacterial or viral infection.

Your immune system then reacts as it would to any infection and tries to eliminate it, either causing a failure to implant or miscarriage.

Immune function is not typically something that a Reproductive Endocrinologist (again, typically referred to as fertility doctors) treats, which is why for some women, there is a potential need to also see a Reproductive Immunologist.

Often times, Reproductive Endocrinologists will work with Reproductive Immunologists remotely, as there aren’t nearly as many Reproductive Immunologists in any one location as there are Reproductive Endocrinologists.

Of course, as I said earlier, most Reproductive Endocrinologists won’t refer you to Reproductive Immunologists, as it’s not common practice, so this might be something you have to seek out on your own.

As I’ve always said, be your own advocate and make sure you’re getting the best care you can. This is your journey.

Tests and Treatments[2]

Most facilities will order Antiphospholipid antibodies (APA) and lupus anticoagulant on patients with recurrent pregnancy loss (RPL).

Other immune tests may be ordered relating to embryo toxic factors and natural killer cells.

Antisperm antibodies, whether cervical, seminal, or plasma, would also likely be ordered in the majority of patients.


As for treatment, the majority of physicians will initiate some form of anticoagulation therapy for patients who tested positive for APA. Many also treat patients with antithyroid antibodies.

The most common treatments are aspirin and steroids, either alone or in combination.

Additional intravenous therapies may be administered when abnormal natural killer cell activity is indicated.

When All Else Fails

When all else fails and you’re at your wits’ end with fertility treatments or the doctor(s) that have been treating you, this may be an avenue you want to consider.

Yes, there is still so much that we are learning about this field, but it has shown positive progress and has helped many women.

If you suspect that there may be something more than what your doctor has been able to find so far, consider looking for a Reproductive Immunologist.

Again, there may not be one located locally, but many are willing to do remote consultations and will work with your local doctors to test and treat you.

[1] Article: Reproductive Immunology: Checkered Past and Bright Future

[2] Article: Immunological testing and treatment in reproduction: frequency assessment of practice patterns at assisted reproduction clinics in the USA and Australia.




More Resources & Products

So now that you’ve read this article, you can put what you’ve learned here into practice immediately and increase your chances of getting pregnant. Here are some additional products and resources to add to your routine that can dramatically improve your fertility. Check them out (limited time discounted packages available)!

Resource 1: Fertility for Her – Essential Oils Roll-On

This proprietary blend of pure, all-natural & organic essential oils was designed to improve your reproductive health, regulating your menstrual cycle and supporting hormonal balance. Fertility for Her™ is formulated for women of all ages, keeping in mind and focusing on women afflicted with unexplained infertility, Endometriosis,  PCOS, and Diminished Ovarian Reserve.

Learn more about Fertility for Her™ by clicking here.

Resource 2: The Cycle Diet

I’ve created a super foods plan that will guide you throughout your cycle and teach you the foods that will significantly boost your fertility.The Cycle Diet is a 28-day system that follows the average woman’s monthly cycle and tells you the optimal foods to be eating during each stage. It teaches you the right food to eat at the right time of your cycle to help regulate ovulation and menstrual cycles, improve egg quality, sooth inflammation and much more…

You can learn more about The Cycle Diet by clicking here.

Resource 3: Fertility Bundles

Are you having trouble getting pregnant or staying pregnant? These bundles were created from one of our best-selling products, The Wolf Method. It includes sections from the e-book that are suited for your specific needs for a more affordable price!

Learn more about our Fertility Bundles by clicking here.

Resource 4: The Wolf Method (TOP SELLING!)

If you don’t want to leave getting pregnant up to chance…and if you feel like there’s more you can be doing right now to get pregnant, take a look at my book called, The Wolf Method.

It’s my 90-day system to get pregnant when you’ve tried all of the traditional methods.

Did you know that the maturation of an egg is a 90 day cycle and what you do in your daily life can DRAMATICALLY impact your egg quality? My book will teach you unique techniques that work.

It also includes sections to help keep your relationship healthy and alive when the stress of trying to conceive can bring you down. Not only this, but this book can save you THOUSANDS of dollars! Click the link below to find out how!

When all else fails, and you need to get pregnant FAST and reliably, use The Wolf Method. Click here to learn more about the book.

Resource 5: Natural Fertility Shop

In order for natural products such as herbs and nutritional supplements to be effective, they must be of the highest quality. This Natural Fertility Shop focuses on offering the best products which are all hand selected by their highly trained fertility specialists from the finest and most reputable companies in the US. Also, all of their products are GMP (good manufacturing practice) certified and they carry certified organic ingredients and products whenever available. Click this link to check them out!


The information in this document has not been evaluated by the FDA and is not intended to diagnose, treat, prevent, or cure any disease.

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